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Distinct Signaling Cascades of TREM-1, TLR and NLR in Neutrophils and Monocytic Cells

Triggering receptor expressed on myeloid cells 1 (TREM-1) is an important mediator of innate inflammatory responses in microbial infections and sepsis. TREM-1 ligation on neutrophils (PMN) or monocytes results in the production of proinflammatory cytokines. Engagement of TREM-1 induces the activatio...

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Detalles Bibliográficos
Publicado en:J Innate Immun
Autores principales: Prüfer, Steve, Weber, Michael, Sasca, Daniel, Teschner, Daniel, Wölfel, Catherine, Stein, Pamela, Stassen, Michael, Schild, Hansjörg, Radsak, Markus P.
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741579/
https://ncbi.nlm.nih.gov/pubmed/24281714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000355892
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