Idelalisib impairs TREM-1 mediated neutrophil inflammatory responses

Triggering receptor expressed on myeloid cells (TREM)-1 on polymorphonuclear neutrophils (PMN) regulates innate immune activation in infectious and non-infectious conditions. TREM-1 ligation activates phosphatidyl-inositol 3 kinase (PI3K) triggering all neutrophil effector functions. As idelalisib i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Alflen, Astrid, Stadler, Nicole, Aranda Lopez, Pamela, Teschner, Daniel, Theobald, Matthias, Heß, Georg, Radsak, Markus P.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882939/
https://ncbi.nlm.nih.gov/pubmed/29615799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23808-2
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker