The Evolutionary History of TLR4 Polymorphisms in Europe

Infections exert important evolutionary pressures shaping the human genome, especially on genes involved in host defense. A crucial step for host defense is recognition of pathogens by pattern recognition receptors on innate immune cells, among which Toll-like receptor 4 (TLR4) is one of the best kn...

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Detalles Bibliográficos
Publicado en:J Innate Immun
Autores principales: Plantinga, Theo S., Ioana, Mihai, Alonso, Santos, Izagirre, Neskuts, Hervella, Montserrat, Joosten, Leo A.B., van der Meer, Jos W.M., de la Rúa, Concepcion, Netea, Mihai G.
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2012
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741577/
https://ncbi.nlm.nih.gov/pubmed/21968286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329492
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