Streptococcal M1 Protein-Provoked CXC Chemokine Formation, Neutrophil Recruitment and Lung Damage Are Regulated by Rho-Kinase Signaling

Streptococcal toxic shock syndrome is frequently caused by Streptococcus pyogenes of the M1 serotype. The aim of this study was to determine the role of Ras-homologous (Rho)-kinase signaling in M1 protein-provoked lung damage. Male C57BL/6 mice received the Rho-kinase-specific inhibitor Y-27632 befo...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Zhang, Songen, Rahman, Milladur, Zhang, Su, Herwald, Heiko, Qi, Zhongquan, Jeppsson, Bengt, Thorlacius, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741568/
https://ncbi.nlm.nih.gov/pubmed/22433673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000336182
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