Transforming Growth Factor-βs Are Essential for the Development of Midbrain Dopaminergic Neurons In Vitro and In Vivo

Development of midbrain dopaminergic neurons is known to depend on inductive signals derived from the ventral midline, including Sonic hedgehog (Shh) as one of the identified molecules. Here we show that in addition to Shh, transforming growth factor (TGF)-β is required for both induction and surviv...

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Vydáno v:J Neurosci
Hlavní autoři: Farkas, Lilla M., Dünker, Nicole, Roussa, Eleni, Unsicker, Klaus, Krieglstein, Kerstin
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2003
Témata:
Development/Plasticity/Repair
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741170/
https://ncbi.nlm.nih.gov/pubmed/12832542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-12-05178.2003
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