Transforming Growth Factor-βs Are Essential for the Development of Midbrain Dopaminergic Neurons In Vitro and In Vivo

Development of midbrain dopaminergic neurons is known to depend on inductive signals derived from the ventral midline, including Sonic hedgehog (Shh) as one of the identified molecules. Here we show that in addition to Shh, transforming growth factor (TGF)-β is required for both induction and surviv...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Farkas, Lilla M., Dünker, Nicole, Roussa, Eleni, Unsicker, Klaus, Krieglstein, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741170/
https://ncbi.nlm.nih.gov/pubmed/12832542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-12-05178.2003
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