The α-Latrotoxin Mutant LTX(N4C) Enhances Spontaneous and Evoked Transmitter Release in CA3 Pyramidal Neurons

α-Latrotoxin (LTX) stimulates vesicular exocytosis by at least two mechanisms that include (1) receptor binding–stimulation and (2) membrane pore formation. Here, we use the toxin mutant LTX(N4C) to selectively study the receptor-mediated actions of LTX. LTX(N4C) binds to both LTX receptors (latroph...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Capogna, Marco, Volynski, Kirill E., Emptage, Nigel J., Ushkaryov, Yuri A.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2003
Fag:
Cellular/Molecular
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741093/
https://ncbi.nlm.nih.gov/pubmed/12764091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-10-04044.2003
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