The α-Latrotoxin Mutant LTX(N4C) Enhances Spontaneous and Evoked Transmitter Release in CA3 Pyramidal Neurons

α-Latrotoxin (LTX) stimulates vesicular exocytosis by at least two mechanisms that include (1) receptor binding–stimulation and (2) membrane pore formation. Here, we use the toxin mutant LTX(N4C) to selectively study the receptor-mediated actions of LTX. LTX(N4C) binds to both LTX receptors (latroph...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Capogna, Marco, Volynski, Kirill E., Emptage, Nigel J., Ushkaryov, Yuri A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741093/
https://ncbi.nlm.nih.gov/pubmed/12764091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-10-04044.2003
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