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Key within-membrane residues and precursor dosage impact the allotopic expression of yeast subunit II of cytochrome c oxidase

Experimentally relocating mitochondrial genes to the nucleus for functional expression (allotopic expression) is a challenging process. The high hydrophobicity of mitochondria-encoded proteins seems to be one of the main factors preventing this allotopic expression. We focused on subunit II of cytoc...

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Publicado en:Mol Biol Cell
Autores principales: Rubalcava-Gracia, Diana, García-Rincón, Juan, Pérez-Montfort, Ruy, Hamel, Patrice Paul, González-Halphen, Diego
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741066/
https://ncbi.nlm.nih.gov/pubmed/31318312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-12-0788
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