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Mitochondrial versus nuclear gene expression and membrane protein assembly: the case of subunit 2 of yeast cytochrome c oxidase

Deletion of the yeast mitochondrial gene COX2, encoding subunit 2 (mtCox2) of cytochrome c oxidase (CcO), results in a respiratory-incompetent Δcox2 strain. For a cytosol-synthesized Cox2 to restore respiratory growth, it must carry the W56R mutation (cCox2(W56R)). Nevertheless, only a fraction of c...

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Publicado en:Mol Biol Cell
Autores principales: Rubalcava-Gracia, Diana, Vázquez-Acevedo, Miriam, Funes, Soledad, Pérez-Martínez, Xochitl, González-Halphen, Diego
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905295/
https://ncbi.nlm.nih.gov/pubmed/29437907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-09-0560
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