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PI3Kβ links integrin activation and PI(3,4)P(2) production during invadopodial maturation
The invasion of tumor cells from the primary tumor is mediated by invadopodia, actin-rich protrusive organelles that secrete matrix metalloproteases and degrade the extracellular matrix. This coupling between protrusive activity and matrix degradation facilitates tumor invasion. We previously report...
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| Published in: | Mol Biol Cell |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6741064/ https://ncbi.nlm.nih.gov/pubmed/31318314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-03-0182 |
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