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Math1 Gene Transfer Generates New Cochlear Hair Cells in Mature Guinea Pigs In Vivo

Hair cell loss in the mammalian cochlea is irreversible and results in permanent hearing loss. Math1, the basic helix-loop-helix transcription factor homolog of the Drosophila atonal gene, is a positive regulator of hair cell differentiation during cochlear development. Developing hair cells express...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kawamoto, Kohei, Ishimoto, Shin-Ichi, Minoda, Ryosei, Brough, Douglas E., Raphael, Yehoash
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740812/
https://ncbi.nlm.nih.gov/pubmed/12805278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-11-04395.2003
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