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Math1 Gene Transfer Generates New Cochlear Hair Cells in Mature Guinea Pigs In Vivo

Hair cell loss in the mammalian cochlea is irreversible and results in permanent hearing loss. Math1, the basic helix-loop-helix transcription factor homolog of the Drosophila atonal gene, is a positive regulator of hair cell differentiation during cochlear development. Developing hair cells express...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Kawamoto, Kohei, Ishimoto, Shin-Ichi, Minoda, Ryosei, Brough, Douglas E., Raphael, Yehoash
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740812/
https://ncbi.nlm.nih.gov/pubmed/12805278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-11-04395.2003
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