The Involvement of Glucose Metabolism in the Regulation of Inducible Nitric Oxide Synthase Gene Expression in Glial Cells: Possible Role of Glucose-6-Phosphate Dehydrogenase and CCAAT/Enhancing Binding Protein

In rat glial cells the lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) gene expression was enhanced by extracellular glucose concentration in a dose-dependent manner. On the other hand, 2-deoxy-d-glucose decreased the LPS-induced iNOS gene expression even in the presence of g...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Won, Je-Seong, Im, Yeong-Bin, Key, Lyndon, Singh, Inderjit, Singh, Avtar K.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740773/
https://ncbi.nlm.nih.gov/pubmed/12930785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-20-07470.2003
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