Brain Region-Specific Mechanisms for Acute Morphine-Induced Mitogen-Activated Protein Kinase Modulation and Distinct Patterns of Activation during Analgesic Tolerance and Locomotor Sensitization

Opioid-receptor activation in cell lines results in phosphorylation of p42/44 mitogen-activated protein kinase (MAPK), which contributes to agonist-induced desensitization of adenylate cyclase signaling. In this study, morphine-induced MAPK modulation was examined in the mouse brain using antibodies...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Eitan, Shoshana, Bryant, Camron D., Saliminejad, Nazli, Yang, Yu C., Vojdani, Elroy, Keith, Duane, Polakiewicz, Roberto, Evans, Christopher J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2003
Ämnen:
Behavioral/Systems/Cognitive
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740691/
https://ncbi.nlm.nih.gov/pubmed/12967998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-23-08360.2003
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