PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation

Transgenic mice, expressing mutant β-amyloid precursor proteins (βAPPs), have lead to a better understanding of the pathophysiological processes in Alzheimer's disease (AD). In many of these models, however, the temporal development of cognitive decline and the relationship to Aβ deposition and...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Richards, J. Grayson, Higgins, Guy A., Ouagazzal, Abdel-Mouttalib, Ozmen, Laurence, Kew, James N. C., Bohrmann, Bernd, Malherbe, Pari, Brockhaus, Manfred, Loetscher, Hansruedi, Czech, Christian, Huber, Gerda, Bluethmann, Horst, Jacobsen, Helmut, Kemp, John A.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2003
Assuntos:
Behavioral/Systems/Cognitive
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740398/
https://ncbi.nlm.nih.gov/pubmed/14523101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-26-08989.2003
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