Age-Dependent Cerebrovascular Abnormalities and Blood Flow Disturbances in APP23 Mice Modeling Alzheimer's Disease

Neuropathological changes associated with Alzheimer's disease (AD) such as amyloidplaques, cerebral amyloid angiopathy, and related pathologies are reproduced in APP23 transgenic mice overexpressing amyloid precursor protein (APP) with the Swedish mutation. Magnetic resonance angiography (MRA)...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Beckmann, Nicolau, Schuler, Alexandra, Mueggler, Thomas, Meyer, Eric P., Wiederhold, Karl-Heinz, Staufenbiel, Matthias, Krucker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Behavioral/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740368/
https://ncbi.nlm.nih.gov/pubmed/13679413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-24-08453.2003
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