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Amyloid-β Immunization Effectively Reduces Amyloid Deposition in FcRγ(-/-) Knock-Out Mice
Direct immunization with amyloidβ protein (Aβ) and passive transfer of anti-Aβ antibodies reduce Aβ accumulation and attenuate cognitive deficits in transgenic models of Alzheimer's disease (AD). The reduction in Aβ deposition has been proposed to involve microglial phagocytosis of Aβ immune co...
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| 發表在: | J Neurosci |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Neuroscience
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6740360/ https://ncbi.nlm.nih.gov/pubmed/13679422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-24-08532.2003 |
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