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Amyloid-β Immunization Effectively Reduces Amyloid Deposition in FcRγ(-/-) Knock-Out Mice

Direct immunization with amyloidβ protein (Aβ) and passive transfer of anti-Aβ antibodies reduce Aβ accumulation and attenuate cognitive deficits in transgenic models of Alzheimer's disease (AD). The reduction in Aβ deposition has been proposed to involve microglial phagocytosis of Aβ immune co...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Das, Pritam, Howard, Victor, Loosbrock, Nicole, Dickson, Dennis, Murphy, M. Paul, Golde, Todd E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740360/
https://ncbi.nlm.nih.gov/pubmed/13679422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-24-08532.2003
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