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Hippocampal cGMP-Dependent Protein Kinase I Supports an Age- and Protein Synthesis-Dependent Component of Long-Term Potentiation But Is Not Essential for Spatial Reference and Contextual Memory

cGMP-dependent protein kinase I (cGKI) is expressed in the hippocampus, but its role in hippocampal long-term potentiation (LTP) is controversial. In addition, whether cGKI is involved in spatial learning has not been investigated. To address these issues, we generated mice with a hippocampus-specif...

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Publié dans:J Neurosci
Auteurs principaux: Kleppisch, Thomas, Wolfsgruber, Wiebke, Feil, Susanne, Allmann, Rüdiger, Wotjak, Carsten T., Goebbels, Sandra, Nave, Klaus-Armin, Hofmann, Franz, Feil, Robert
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740356/
https://ncbi.nlm.nih.gov/pubmed/12853418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-14-06005.2003
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