Identifying Compounds with Genotoxicity Potential Using Tox21 High Throughput Screening Assays

Genotoxicity is a critical component of a comprehensive toxicological profile. The Tox21 Program used five quantitative high throughput screening (qHTS) assays measuring some aspect of DNA damage/repair to provide information on the genotoxic potential of over 10,000 compounds. Included were assays...

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Bibliographic Details
Published in:Chem Res Toxicol
Main Authors: Hsieh, J-H, Smith-Roe, SL, Huang, R, Sedykh, A, Shockley, KR, Auerbach, SS, Merrick, BA, Xia, M, Tice, RR, Witt, KL
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740247/
https://ncbi.nlm.nih.gov/pubmed/31243984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00053
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