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PKCδ requires p53 for suppression of the transformed phenotype in human colon cancer cells
We have previously demonstrated that the delta isoform of Protein Kinase C (PKCδ) acts as a tumor suppressor in HCT116 human colon cancer cells, and that p21(waf1/cip1) is an essential downstream effector of PCKδ. Our data suf‐fested that p53 might also be involved in the suppression of the neoplast...
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6740212/ https://ncbi.nlm.nih.gov/pubmed/15601585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2004.tb00481.x |
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