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PKCδ-MEDIATED REGULATION OF FLIP EXPRESSION IN HUMAN COLON CANCER CELLS
FLICE-like inhibitory protein (FLIP), a naturally occurring caspase-inhibitory protein that lacks the critical cysteine domain necessary for catalytic activity, is a negative regulator of Fas-induced apoptosis. Decreased FLIP levels sensitize tumor cells to Fas- and TRAIL-mediated apoptosis; however...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850992/ https://ncbi.nlm.nih.gov/pubmed/16052516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.21373 |
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