PKCδ-MEDIATED REGULATION OF FLIP EXPRESSION IN HUMAN COLON CANCER CELLS

FLICE-like inhibitory protein (FLIP), a naturally occurring caspase-inhibitory protein that lacks the critical cysteine domain necessary for catalytic activity, is a negative regulator of Fas-induced apoptosis. Decreased FLIP levels sensitize tumor cells to Fas- and TRAIL-mediated apoptosis; however...

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Hlavní autoři: Wang, Qingding, Wang, Xiaofu, Zhou, Yuning, Evers, B Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850992/
https://ncbi.nlm.nih.gov/pubmed/16052516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.21373
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