VHH characterization. Comparison of recombinant with chemically synthesized anti‐HER2 VHH

In the continuous exploration of the VHH chemistry, biochemistry and therapeutic future use, we investigated two different production strategies of this small antibody‐like protein, using an anti‐HER2 VHH as a model. The total chemical synthesis of the 125 amino‐acid peptide was performed with reaso...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Hartmann, Lucie, Botzanowski, Thomas, Galibert, Mathieu, Jullian, Magali, Chabrol, Eric, Zeder‐Lutz, Gabrielle, Kugler, Valérie, Stojko, Johann, Strub, Jean‐Marc, Ferry, Gilles, Frankiewicz, Lukasz, Puget, Karine, Wagner, Renaud, Cianférani, Sarah, Boutin, Jean A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Full‐Length Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739820/
https://ncbi.nlm.nih.gov/pubmed/31423659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3712
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