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Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial

BACKGROUND: Intrahepatic cholestasis of pregnancy, characterised by maternal pruritus and increased serum bile acid concentrations, is associated with increased rates of stillbirth, preterm birth, and neonatal unit admission. Ursodeoxycholic acid is widely used as a treatment without an adequate evi...

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Podrobná bibliografie
Vydáno v:Lancet
Hlavní autoři: Chappell, Lucy C, Bell, Jennifer L, Smith, Anne, Linsell, Louise, Juszczak, Edmund, Dixon, Peter H, Chambers, Jenny, Hunter, Rachael, Dorling, Jon, Williamson, Catherine, Thornton, Jim G
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739598/
https://ncbi.nlm.nih.gov/pubmed/31378395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(19)31270-X
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