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Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES)

BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder specific to pregnancy and presents with maternal pruritus, raised concentrations of serum bile acids and abnormal liver function tests. ICP is associated with increased rates of spontaneous and iatrogenic prete...

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Bibliografiske detaljer
Udgivet i:Trials
Main Authors: Chappell, Lucy C., Chambers, Jenny, Dixon, Peter H., Dorling, Jon, Hunter, Rachael, Bell, Jennifer L., Bowler, Ursula, Hardy, Pollyanna, Juszczak, Edmund, Linsell, Louise, Rounding, Catherine, Smith, Anne, Williamson, Catherine, Thornton, Jim G.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260710/
https://ncbi.nlm.nih.gov/pubmed/30482254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-018-3018-4
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