Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling

The novel antibody-based immunotherapy in oncology exploits the activation of immune system mediated by immunomodulatory antibodies specific for immune checkpoints. Among them, the programmed death ligand-1 (PD-L1) is of particular interest as it is expressed not only on T-cells, but also on other i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Passariello, Margherita, D’Alise, Anna Morena, Esposito, Annachiara, Vetrei, Cinzia, Froechlich, Guendalina, Scarselli, Elisa, Nicosia, Alfredo, De Lorenzo, Claudia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739323/
https://ncbi.nlm.nih.gov/pubmed/31511565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49485-3
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