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Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments

SIMPLE SUMMARY: A novel challenge in cancer immunotherapy is the identification of the most potent combinations of immunomodulatory mAbs that are capable of maximizing therapeutic benefits while minimizing irAEs. We set up an in vitro system to quickly predict the efficacy and eventual cardiotoxic s...

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Publicado en:Cancers (Basel)
Main Authors: Vetrei, Cinzia, Passariello, Margherita, Froechlich, Guendalina, Rapuano Lembo, Rosa, Zambrano, Nicola, De Lorenzo, Claudia
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230074/
https://ncbi.nlm.nih.gov/pubmed/34201082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13122858
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