The molecular basis of chaperone-mediated interleukin 23 assembly control

The functionality of most secreted proteins depends on their assembly into a defined quaternary structure. Despite this, it remains unclear how cells discriminate unassembled proteins en route to the native state from misfolded ones that need to be degraded. Here we show how chaperones can regulate...

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Publicado no:Nat Commun
Main Authors: Meier, Susanne, Bohnacker, Sina, Klose, Carolin J., Lopez, Abraham, Choe, Christian A., Schmid, Philipp W. N., Bloemeke, Nicolas, Rührnößl, Florian, Haslbeck, Martin, Bieren, Julia Esser-von, Sattler, Michael, Huang, Po-Ssu, Feige, Matthias J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739322/
https://ncbi.nlm.nih.gov/pubmed/31511508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12006-x
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