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Assembly-induced folding regulates interleukin 12 biogenesis and secretion

Members of the IL-12 family perform essential functions in immunoregulation by connecting innate and adaptive immunity and are emerging therapeutic targets. They are unique among other interleukins in forming heterodimers that arise from extensive subunit sharing within the family, leading to the pr...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Reitberger, Susanne, Haimerl, Pascal, Aschenbrenner, Isabel, Esser-von Bieren, Julia, Feige, Matthias J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427282/
https://ncbi.nlm.nih.gov/pubmed/28325840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782284
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