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Multiplex PCR of three dinucleotide repeats in the Prader–Willi/Angelman critical region (15q11–q13): molecular diagnosis and mechanism of uniparental disomy

Prader−Willi syndrome (PWS) and Angelman syndrome (AS) are distinct mental retardation disorders caused by a deficiency of paternal (PWS) or maternal (AS) contributions for chromosome 15 by either deletion or uniparental disomy (UPD). To further study the molecular mechanisms involved in these disor...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Mutirangura, Apiwat, Greenberg, Frank, Butler, Merlin G., Malcolm, Sue, Nicholls, Robert D., Chakravarti, Aravinda, Ledbetter, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739235/
https://ncbi.nlm.nih.gov/pubmed/8499903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/2.2.143
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