Identification of Antibiotic Administration as a Potentially Novel Factor Associated With Tacrolimus Trough Variability in Kidney Transplant Recipients: A Preliminary Study

Tacrolimus trough variability is an important risk factor for kidney allograft outcomes. Recent evidence suggests that the gut microbiota is associated with tacrolimus dosing requirements and direct metabolism of tacrolimus. We hypothesize that administration of antibiotics, which are known to alter...

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Vydáno v:Transplant Direct
Hlavní autoři: Zheng, YuanPu, Masand, Anjali, Wagner, Michael, Kapur, Sandip, Dadhania, Darshana, Lubetzky, Michelle, Lee, John Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Health 2019
Témata:
Kidney Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739039/
https://ncbi.nlm.nih.gov/pubmed/31579813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000930
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