Identification of Antibiotic Administration as a Potentially Novel Factor Associated With Tacrolimus Trough Variability in Kidney Transplant Recipients: A Preliminary Study

Tacrolimus trough variability is an important risk factor for kidney allograft outcomes. Recent evidence suggests that the gut microbiota is associated with tacrolimus dosing requirements and direct metabolism of tacrolimus. We hypothesize that administration of antibiotics, which are known to alter...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transplant Direct
Hauptverfasser: Zheng, YuanPu, Masand, Anjali, Wagner, Michael, Kapur, Sandip, Dadhania, Darshana, Lubetzky, Michelle, Lee, John Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Health 2019
Schlagworte:
Kidney Transplantation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739039/
https://ncbi.nlm.nih.gov/pubmed/31579813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000930
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