Combined Stimulation with Interleukin-18 and Interleukin-12 Potently Induces Interleukin-8 Production by Natural Killer Cells

The combination of interleukin (IL)-18 and IL-12 (IL-18+IL-12) potently stimulates natural killer (NK) cells, triggering an innate immune response to infections and cancers. Strategies exploiting the effects of IL-18+IL-12 have shown promise for cancer immunotherapy. However, studies have primarily...

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Udgivet i:J Innate Immun
Main Authors: Poznanski, Sophie M., Lee, Amanda J., Nham, Tina, Lusty, Evan, Larché, Margaret J., Lee, Dean A., Ashkar, Ali A.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738883/
https://ncbi.nlm.nih.gov/pubmed/28633138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000477172
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