Tissue-Specific Regulation of Drosophila NF-κB Pathway Activation by Peptidoglycan Recognition Protein SC

In Drosophila, peptidoglycan (PGN) is detected by PGN recognition proteins (PGRPs) that act as pattern recognition receptors. Some PGRPs such as PGRP-LB or PGRP-SCs are able to cleave PGN, therefore reducing the amount of immune elicitors and dampening immune deficiency (IMD) pathway activation. The...

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Veröffentlicht in:J Innate Immun
Hauptverfasser: Costechareyre, Denis, Capo, Florence, Fabre, Alexandre, Chaduli, Delphine, Kellenberger, Christine, Roussel, Alain, Charroux, Bernard, Royet, Julien
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738878/
https://ncbi.nlm.nih.gov/pubmed/26513145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000437368
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