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A Novel Pathway of Cell Death in Response to Cytosolic DNA in Drosophila Cells

Defence against invading DNA occurs in both mammals and bacteria. Recognition of stray DNA can initiate responses to infection, but may also protect against potentially mutagenic integration of transposons or retrotransposons into the genome. Double-stranded DNA detected in the cytosol of mammalian...

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Bibliographische Detailangaben
Veröffentlicht in:J Innate Immun
Hauptverfasser: Vitak, Nazarii, Johnson, Karyn N., Sester, David P., Stacey, Katryn J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738762/
https://ncbi.nlm.nih.gov/pubmed/25472853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000368276
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