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A Novel Pathway of Cell Death in Response to Cytosolic DNA in Drosophila Cells

Defence against invading DNA occurs in both mammals and bacteria. Recognition of stray DNA can initiate responses to infection, but may also protect against potentially mutagenic integration of transposons or retrotransposons into the genome. Double-stranded DNA detected in the cytosol of mammalian...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Vitak, Nazarii, Johnson, Karyn N., Sester, David P., Stacey, Katryn J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738762/
https://ncbi.nlm.nih.gov/pubmed/25472853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000368276
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