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The direction of chain growth and substrate preferences of SEDS-family peptidoglycan glycosyltransferases

The bacterial cell wall is composed of peptidoglycan, and its biosynthesis is an established target for antibiotics. Peptidoglycan is assembled from a glycopeptide precursor, Lipid II, that is polymerized by peptidoglycan glycosyltransferases into glycan strands that are subsequently crosslinked to...

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Publicat a:J Am Chem Soc
Autors principals: Welsh, Michael A., Schaefer, Kaitlin, Taguchi, Atsushi, Kahne, Daniel, Walker, Suzanne
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738341/
https://ncbi.nlm.nih.gov/pubmed/31386359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b06358
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