Down Regulation of c-FLIP(L) Enhance PD-1 Blockade Efficacy in B16 Melanoma

Immune checkpoint blockade of programmed cell death protein 1 (PD-1) had an impressive long-lasting effect in a portion of advanced-stage melanoma patients, however, this therapy failed to induce responses in several patients; how to increase the objective response rate is very important. Cellular F...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Wang, Yao, Li, Jing-jing, Ba, Hong-jun, Wang, Ke-feng, Wen, Xi-zhi, Li, Dan-dan, Zhu, Xiao-feng, Zhang, Xiao-shi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738195/
https://ncbi.nlm.nih.gov/pubmed/31552181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00857
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