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Exploring the best treatment options for BRAF-mutant metastatic colon cancer
The BRAF(V600E) mutation is a well-accepted poor prognostic factor in patients with metastatic colorectal cancer (mCRC), as it confers Ras-independent stimulation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway involved in proliferation, migration, angiogenesis...
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| 發表在: | Br J Cancer |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6738120/ https://ncbi.nlm.nih.gov/pubmed/31353365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0526-2 |
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