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Role of Dach1 revealed using a novel inner ear-specific Dach1-knockdown mouse model

The Dach1 gene is expressed in the inner ear of normal mouse embryos in the area that differentiates into the cochlear stria vascularis (SV). We hypothesised that Dach1 downregulation in the inner ear would lead to SV dysplasia. However, because Dach1 knockout is embryonic lethal in mice, the role o...

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Detaylı Bibliyografya
Yayımlandı:Biol Open
Asıl Yazarlar: Miwa, Toru, Minoda, Ryosei, Ishikawa, Yoshihide, Kajii, Tomohito, Orita, Yorihisa, Ohyama, Takahiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737983/
https://ncbi.nlm.nih.gov/pubmed/31405829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.043612
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