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Prenatal electroporation-mediated gene transfer restores Slc26a4 knock-out mouse hearing and vestibular function

The otocyst, an anlage of the inner ear, presents an attractive target to study treatment strategies for genetic hearing loss and inner ear development. We have previously reported that electroporation-mediated transuterine gene transfer of Connexin30, utilizing a monophasic pulse into Connexin30(−/...

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書目詳細資料
發表在:Sci Rep
Main Authors: Takeda, Hiroki, Miwa, Toru, Kim, Min Young, Choi, Byung Yoon, Orita, Yorihisa, Minoda, Ryosei
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884448/
https://ncbi.nlm.nih.gov/pubmed/31784581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54262-3
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