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MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis

Melanoma with rapid progression towards metastasis has become the deadliest form of skin cancer. However, the mechanism of melanoma growth and metastasis is still unclear. Here, we found that miRNA-138 was lowly expressed and hypoxia-inducible factor 1α (HIF1α) was highly expressed in patients’ mela...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Qiu, Haijiang, Chen, Fangchao, Chen, Minjun
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737980/
https://ncbi.nlm.nih.gov/pubmed/31371307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.042937
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