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MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis

Melanoma with rapid progression towards metastasis has become the deadliest form of skin cancer. However, the mechanism of melanoma growth and metastasis is still unclear. Here, we found that miRNA-138 was lowly expressed and hypoxia-inducible factor 1α (HIF1α) was highly expressed in patients’ mela...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biol Open
Hauptverfasser: Qiu, Haijiang, Chen, Fangchao, Chen, Minjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737980/
https://ncbi.nlm.nih.gov/pubmed/31371307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.042937
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