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High-Affinity Nucleic-Acid-Based Receptors for Steroids

Artificial receptors for hydrophobic molecules usually have moderate affinities and limited selectivities. We describe three new classes of high affinity hydrophobic receptors for non-aromatic steroids based on deoxyribonucleotides, obtained through five high stringency selections coupled with tailo...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Yang, Kyung-Ae, Chun, Hyosun, Zhang, Yameng, Pecic, Stevan, Nakatsuka, Nako, Andrews, Anne M., Worgall, Tilla S., Stojanovic, Milan N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737899/
https://ncbi.nlm.nih.gov/pubmed/29083858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00634
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