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Sodium Diisopropylamide-Mediated Dehydrohalogenations: Influence of Primary- and Secondary-Shell Solvation

[Image: see text] Eliminations of alkyl halides by sodium diisopropylamide (NaDA) in tetrahydrofuran (THF)/hexane or THF/N,N-dimethylethylamine (DMEA) solutions are facile and complementary to analogous reactions of lithium diisopropylamide in THF. Rate studies show a dominance of monomer-based meta...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Ma, Yun, Algera, Russell F., Woltornist, Ryan A., Collum, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737842/
https://ncbi.nlm.nih.gov/pubmed/31436099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b01428
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