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Two Chinese nephronophthisis pedigrees harbored a compound heterozygous deletion with a point mutation in NPHP1

NPHP1 is the most prevalent genetic factor in the development of juvenile nephronophthisis (NPHP). In our previous study, NPHP1 homozygous point mutations were detected by Sanger sequencing in three cases from two nonconsanguineous pedigrees. However, mutant sites were detected in only one parent fr...

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Podrobná bibliografie
Vydáno v:Int J Mol Epidemiol Genet
Hlavní autoři: Chen, Huamu, Lin, Hongrong, Yue, Zhihui, Wang, Haiyan, Yang, Junhui, Sun, Liangzhong
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737400/
https://ncbi.nlm.nih.gov/pubmed/31523374
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