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Mouse model of severe recessive RYR1-related myopathy

Ryanodine receptor type I (RYR1)-related myopathies (RYR1 RM) are a clinically and histopathologically heterogeneous group of conditions that represent the most common subtype of childhood onset non-dystrophic muscle disorders. There are no treatments for this severe group of diseases. A major barri...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Brennan, Stephanie, Garcia-Castañeda, Maricela, Michelucci, Antonio, Sabha, Nesrin, Malik, Sundeep, Groom, Linda, Wei LaPierre, Lan, Dowling, James J, Dirksen, Robert T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737254/
https://ncbi.nlm.nih.gov/pubmed/31107960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz105
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