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Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype
Conformational changes of major histocompatibility complex (MHC) antigens have the potential to be recognized by T cells and may arise from polymorphic variation of the MHC molecule, the binding of modifying ligands, or both. Here, we investigated whether metal ions could affect allele-dependent str...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737219/ https://ncbi.nlm.nih.gov/pubmed/31296658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008937 |
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